Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2
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منابع مشابه
Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6.
In the CNS, the lack of the transcription factor Pax6 has been associated with early defects in cell proliferation, cell specification, and axonal pathfinding of discrete neuronal populations. In this study, we show that Pax6 is expressed in discrete catecholaminergic neuronal populations of the developing ventral thalamus, hypothalamus, and telencephalon. In mice lacking Pax6, these catecholam...
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SJNCE the first open intracardiac repair of interventricular septal defects and tetralogy of Fallot,1 2 rapid progress has been made in operative technics and in extracorporeal perfusion technology. Operative risk has steadily declined, and recent communications indicate that in ventricular septal defects uncomplicated by pulmonary hypertention the mortality rate is approximately 2 per cent.3 5...
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Ventricular septal defects account for up to 40% of all congenital cardiac malformations. The diagnosis encompasses a broad range of anomalies, including isolated defects and those associated with other congenital cardiac malformations. Presentation, symptoms, natural history, and management of ventricular septal defects depend on size and anatomical associations of the anomaly, patient's age, ...
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Ventricular septal defect (VSD) is the persistence of one or more holes in the septum that separates the left and right ventricles of the heart. The ventricles are a single chamber at about four weeks of gestation but by eight weeks it has been divided into two. Failure of development of any part of the septum results in a defect. It may vary considerably in terms of size and haemodynamic conse...
متن کاملSmall Ventricular Septal Defect
T HE auscultatory and phonocardiographic characteristics of ventricular septal defects have been the subject of several studies,'-5 none of them dealing specifically with the features of small defects. The present study represents an attempt to define the phonocardiographic pattern of ventricular septal defect with a small left-to-right shunt and normal pulmonary artery pressure. It was hoped t...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.252648999